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Combating Resistance To Targeted Anticancer Therapies Via Caspase-3-Mediated MEK Degradation

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Increasingly, anticancer drugs targeting mutant or fusion proteins found in a patient’s tumor are becoming the gold standard for modern-day cancer treatment. This personalized approach…
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Disrupting The Brain Keeper To Allow Silencing Of Deleterious Genes In The Nervous System

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Therapeutic oligonucleotides, such as small interfering RNAs (siRNA), hold great promise for the treatment of genetically-defined disorders, including diseases of the central nervous system (CNS)….
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ORC Technology For Residential Applications

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The last decades of worldwide social, economic, and technological developments have led to an increase in the number of people requesting energy-consuming living amenities. This…
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3D Green Peanut Hull/Graphene Aerogels For Highly Efficient Oil-Water Separation

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Graphene is a very amazing material for its unique gapless conical band structure, its efficient wide range of light absorption, its high mechanical strength, flexibility,…
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Breaking Bad: IgG4 In Autoimmunity

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The human immune system is a complex network of cells and soluble factors that can cleverly adapt to combat infection.  For example, B cells rearrange…
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Recent Study Shows That Bacteria And Fungi In The Gut Of Babies Are Linked To Future Asthma Risk

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What causes asthma? At a time when global rates of asthma have reached alarming rates, this important question remains unanswered. This debilitating disease affects approximately…
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On/Off Switching During The Synthesis Of Complex Sugars

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Glycosylation is the ubiquitous, highly-regulated process by which carbohydrate is added to proteins and lipids to form glycoconjugates (glycans). These carbohydrate portions of glycans can…
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Environmental Remediation And Energy Reclamation From Natural Water Matrices And Wastewater By Solar Photocatalytic Technology

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Both water and energy are key sustainability issues that need to be addressed. To this end, photocatalysis is advantageous not only for expediting environmental remediation…
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How Human Activities Have Modified Nitrogen And Phosphorus Delivery To Global Rivers

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Nitrogen (N) and phosphorus (P) are both essential nutrients, indispensable for living species to survive and grow. They are naturally present in the environment and…
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Exploring The Thermoelectric Properties Of Transition Metal Chalcogenides: TcX2(X=S, Se, Te)

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Transition metal chalcogenides (TMCs) as potential candidates for application in thermoelectric conversion field have been attracted a lot of attention. TcX2(X=S, Se, Te) are also…
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How Do You Rapidly Feed A Hungry Brain?

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The remarkable computing capacity of the brain has roots in the structural and functional design features of neurons, glia and the circuits they form. Electrical…
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