Meta-Sulfamoyl N-Hydroxybenzamides As HDAC8-Selective Inhibitors
As a family of epigenetic enzymes, histone deacetylases (HDACs) can catalyze the removal of an acetyl group from N-acetyl lysine residues of histones and other…
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Current Knowledge Of Lepidoptera Genomes And Future Directions
Science is often advanced with the development of new technologies. Since the sequencing of the first human genome, there has been much progress made in…
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The Inactive X Chromosome Is Folded Like Origami By SMCHD1
The linear molecules of DNA that constitute our genome are wrapped around proteins called histones to form “chromatin.” To fit the nucleus, chromatin must be…
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Lead Iodide Nanosheets For Piezoelectric Energy Conversion And Strain Sensing
Harvesting ambient mechanical energy or sensing the mechanical signals based on nanomaterials for self-powered and flexible systems can provide potentially revolutionary advancements in energy technologies….
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Racial Disparity In Surgery For Esophageal Cancer
Surgery for esophageal cancer (esophagectomy) is considered standard of care for patients with early-stage disease and can provide long-term survival benefits to the patients. These…
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Adverse Events Following Coronary Angiography And Cardiac Surgery
Having a major adverse renal or cardiac event (MARCE) is a calculable risk following cardiac surgery. As techniques for percutaneous coronary interventions (PCI) have improved…
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Measuring The Water And Energy In An Alpine Peatland
Peatlands are wetlands with at least a 30-40 cm thick peat layer and are highly dependent on water. In these waterlogged, anaerobic soils, the dead…
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Concentric Crater Fill: How Martian Craters Filled With Ice And Why It’s Still There
Many mid-latitude impact craters on Mars are filled to variable degrees with a combination of ice, dust, and rocky debris. Ring-shaped surface features visible in…
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The Use Of Mobile Health (mHealth) For Increasing Physical Activity And Fitness In Cardiovascular Disease Populations
Coronary artery disease (CAD) and peripheral artery disease (PAD) are diseases of atherosclerosis that have enormous clinical and economic burden in the United States. Adherence…
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Why We Get Frail And How To Reverse It
Aging is characterized by a gradual loss of cellular homeostasis and tissue function. This is a major cause of frailty in the elderly, which reduces their quality…
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Exploring The Moon’s Iron Distribution
The moon is considered to have experienced a magma ocean, with whole-body melting. Differentiation and crystallization of the melt formed today’s crustal Moon. Major elemental…
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