Aminoacyl-tRNA synthetases (aaRSs) are a family of ancient enzymes. Their primary function is to build proteins by loading up the proper amino acids to charging…
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Preterm Birth (PTB), a human birth happening before 37 completed weeks of gestation, is a leading cause of infant mortality and morbidity. PTB babies tend…
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Increasingly, anticancer drugs targeting mutant or fusion proteins found in a patient’s tumor are becoming the gold standard for modern-day cancer treatment. This personalized approach…
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The human immune system is a complex network of cells and soluble factors that can cleverly adapt to combat infection. For example, B cells rearrange…
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In Canada, approximately 3% of all traumatic injuries result in peripheral nerve damage resulting in many patients suffering from lifelong sensorimotor impairments. In severe cases,…
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There are many reports on the management of problematic skin wounds with a compromised skin barrier. The burden is growing rapidly, with almost six million…
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The overall prevalence of depression among the older population is around 7% and, hence, is a major health issue. Depression may be associated with global…
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Glycosylation is the ubiquitous, highly-regulated process by which carbohydrate is added to proteins and lipids to form glycoconjugates (glycans). These carbohydrate portions of glycans can…
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There is evidence for long-lasting negative effects of adverse birth characteristics such as low birth weight, short birth length, small head circumference, preterm birth, and…
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What causes asthma? At a time when global rates of asthma have reached alarming rates, this important question remains unanswered. This debilitating disease affects approximately…
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Neurological disorders remain one of the last frontiers of medicine. Available treatments are few; of those that exist, most only mitigate symptoms and do nothing…
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