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A New Mechanism Of Immune Regulation That Limits The Efficacy Of Immunotherapy

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Immunotherapy with checkpoint blockade has revolutionized cancer treatment in the last decade. With the initial FDA approval of CTLA-4 blockade with ipilimumab in 2011 followed…
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Properties Of Point Defects In Nuclear Fuel Crystal Lattice

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Nuclear energy has immense potential because uranium and other actinides are the most energy-dense resources available. For instance, only a few grams of uranium dioxide…
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Cognitive Rehabilitation Techniques To Treat Schizophrenia

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The impairment of basic cognition and social cognition is a well-established feature of schizophrenia. Basic cognition includes cognitive domains such as attention, information processing speed,…
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Obstacles To Renewable Energy Adoption In Colombia

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Colombia is one of the main emerging economies of the South American continent and that means an ever-growing energy demand. In particular, electricity consumption is…
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Personalized Medicine And Why We Are Not There Yet

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Traditionally, medicine has been based on the disease and not the patient. This means that for the same disease, e.g. childhood leukemia, two very different…
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How Combining Structurally Different RAF Inhibitors Can Open New Strides In Targeted Melanoma Therapy

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Malignant melanoma is a skin cancer primarily caused by overexposure to UV rays from the sun or tanning beds. Unfortunately, the number of skin cancers…
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Reactive Muscle Precursor Cells In The Lens Contribute To Formation Of Secondary Cataracts

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Millions of individuals undergo cataract surgery each year. Although removal of cataracts restores vision, approximately 20% of adults and most children develop a re-clouding of…
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Not All Watersheds Are Created Equal: Natural Boundaries Also Predict Patterns Of Inequality

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Patterns of inequality in exposure to environmental pollutants exist around the world today, even right here in our backyards. Such patterns of injustice, observed over…
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Flying To The Tune Of A Neuropeptide Receptor: “Exciting” Insights From Fruit Flies

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For a fruit fly, flying is just about everything. It is the most important innate behavior that helps the fly reach out to food sources…
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Feeding Electricity To Bacteria

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Can electricity serve as an alternative electron supplier for bacterial growth? And can we enhance the electron uptake capacity of bacteria? Bacteria utilize both organic…
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Mechanisms By Which Probiotics Act On The Human Brain Still Elude Us, But We’re Getting Closer

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By definition, anything that’s called a probiotic must produce a scientifically demonstrated health effect. And in theory, this could be a brain health effect. We…
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