A Closer Look At The Fusion Machinery Of A Herpesvirus
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About The Author

Z. Hong Zhou is a professor in the Department of Microbiology, Immunology and Molecular Genetics, the Department of Bio-engineering and the Director of the Electron Imaging Center for Nanomachines of California NanoSystems Institute at University of California, Los Angeles.

                       

A Closer Look At The Fusion Machinery Of A Herpesvirus

Infection by herpesviruses leads to many human diseases, ranging from a cold sore, chickenpox, to cancer. Human cytomegalovirus (HCMV) is a member of the β-herpesvirus subfamily of the Herpesviridae, with a high seroprevalence in the global human population via direct contact with bodily secretions, ranging from 50% in industrialized countries to as high as 99% in resource-poor communities and developing countries. HCMV is the leading viral cause of birth defects and is often responsible for life-threatening complications among immunocompromised individuals....

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