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Yingjie Zhang

Yingjie Zhang is an associate professor at the Shandong University School of Pharmaceutical Sciences. his research interests include rational design, synthesis and biological evaluation of compounds targeting histone deacetylase (HDAC), aminopeptidase (AP) and protein kinases.

Meta-Sulfamoyl N-Hydroxybenzamides As HDAC8-Selective Inhibitors

As a family of epigenetic enzymes, histone deacetylases (HDACs) can catalyze the removal of an acetyl group from N-acetyl lysine residues of histones and other proteins. The human HDACs can be grouped into 4 classes based on their homology to […]