Differences In α-Crystallin Isomerization In The Human Eye Lens Expose New Details About Aging
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About The Author

Dr. Yana Lyon currently works at the Department of Chemistry , University of California, Riverside. Yana does research in Bioanalytical Chemistry. Their most recent publication is 'The Ups and Downs of Repeated Cleavage and Internal Fragment Production in Top-Down Proteomics.'

                       

Differences In α-Crystallin Isomerization In The Human Eye Lens Expose New Details About Aging

Proteins are susceptible to spontaneous chemical degradation that can occur on timescales ranging from hours to decades, which may explain why the half-lives for many proteins are measured in days. At the same time, protein recycling is energetically inefficient and, in many cases, implausible. This makes the existence of long-lived proteins (LLPs) inevitable. Indeed, LLPs have been detected in tissue from the brain, eyes, skin, teeth, muscle, and heart, with residence times ranging from months to entire lifetimes. Many LLPs...

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