Inactivation Of Serine Racemase: A Possible Treatment Strategy For Diabetic Retinopathy
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About The Author

Shengzhou Wu is a professor at Wenzhou Medical University in the School of Optometry and Ophthalmology.  Their research focuses on neurodegeneration and diabetic retinopathy. He has authored over 30 peer-reviewed publications and has 2000 citations.

                       

Inactivation Of Serine Racemase: A Possible Treatment Strategy For Diabetic Retinopathy

Diabetic retinopathy (DR) is a leading cause of adult blindness and a deleterious complication of diabetes mellitus. After a decade of diabetes, ~80-90% of patients develop DR, in which ~ 5-10% of them develop blindness due to macular edema, retinal neovascularization, and others. At the early stage of DR called non-proliferative DR, patients have no clinical symptoms, but the typical pathologies such as retinal ganglion cell loss, degeneration of retinal nerve fiber, as well as pericyte loss, change the permeability...

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