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pH Rules The Fate Of Chitosan-Based Complexes

Chitosan, the second-most abundant natural polysaccharide, is a cationic polymer widely used for the preparation of particles, hydrogels, or scaffolds intended for biomedical purposes [1,2]. All these intensively studied platforms are typically formed by electrostatic interaction between a positively charged chitosan and negatively charged complexing agent. Their biocompatibility, biodegradability, as well as tunable properties, make chitosan-based