A Novel Approach To Identify Genetic Signatures Of Clinical Outcome To Ipilimumab
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Physician-scientist engaged in exploring tumor-immune interactions through next-generation sequencing to discover novel insights into immune-evasion and translate molecular signatures predictive of immunotherapeutic response to the clinic.

                       

A Novel Approach To Identify Genetic Signatures Of Clinical Outcome To Ipilimumab

Immune therapies focused on unleashing the body’s own immune system against cancer have heralded a revolution in clinical oncology. Dramatic responses are now being observed in several intractable tumor types like metastatic melanomas which were previously associated with very short survival times. At the forefront of this revolution are cancer immunotherapy drugs known as “checkpoint inhibitors.” In a healthy individual, small tumors that arise in the body are continually detected and eliminated by the immune system. In cancer patients, however,...

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