Autophagy Declares The Clean Bill Of A Cell’s Health
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Palaniyandi is a research scientist at the Vellore Institute of Technology.

                       

Autophagy Declares The Clean Bill Of A Cell’s Health

The term “Autophagy”, originating from the Greek words “auto” (meaning self) and “phagy” (meaning eat) is the evolutionarily conserved physiological process that maintains the protein turnover within a cell. The mechanism involves the formation of double-membrane vesicles called autophagosomes to encapsulate the misfolded proteins, invading pathogens and other dysfunctional cytoplasmic constituents. These constituents of autophagosome are collectively called as cargo which is delivered into the lysosomal compartment for degradation. The machinery of autophagy involves around 30 genes which are called...

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