Improved Stability Of Live, Attenuated Vaccine gdhA Derivative Pasteurella Multocida B:2 By Freeze Drying Technique
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About The Author

Murni Halim is a senior lecturer at the Department of Bioprocess Technology, Faculty of Biotechnology and Biomolecular Sciences, Universiti Putra Malaysia (UPM) since January, 2013. She is also a Research Associate at the Bioprocessing and Biomanufacturing Research Centre (BBRC), UPM. She was graduated with a Bachelor of Engineering (Biotechnology/ Biochemical) from International Islamic University Malaysia in 2006. She then obtained her MSc in Biochemical Engineering from University College London (UCL), United Kingdom in 2008. In 2012, she obtained her PhD (Biochemical Engineering) also from UCL. Her research projects are mainly related to the development of bioprocessing and biomanufacturing processes for productions of various biotechnology products.

                       

Improved Stability Of Live, Attenuated Vaccine gdhA Derivative Pasteurella Multocida B:2 By Freeze Drying Technique

The use of live attenuated vaccine gdhA derivative Pasteurella multocida B:2 that can be administered intranasally is an alternative way to protect cattle and buffaloes from hemorrhagic septicaemi disease and increase vaccination coverage. Despite its proven record, however, there has been limited success in the development of a commercial live attenuated vaccine that is associated with the difficulty in maintaining the stability during long-term storage and the possibility of temperature variations during shipment. The live attenuated vaccine mutant P. multocida B:2...

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