Towards The Engineering Of Living Cells That Mimic Computers
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About The Author

I graduated in Biology (BSc. Biology (Hons)), at the University of Jaén in Spain in 2006. During this period I was a trainee in the Department of Genetics. This experience was extremely formative, as it allowed to me to gain experience in basic techniques in genomics and molecular biology. The major aim of the research during my PhD period was to characterization of higher molecular thiols in biological samples by matrix assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF). My educational background reflects multidisciplinary experiences, as it includes human biology, human genomic, microbiology, mass spectrometry and proteomic in a unique multidisciplinary approach including state-of-the-art technologies and methodologies.

Currently, my work focuses on: (1) Identify potential new markers to open up the possibility of performing an analysis of individual prostate cancer specimens in order to estimate the individual metastatic potential of each patient in the future, (2) The influences expression of genes involve in oncogene-induced senescence and cell cycle after hMT-3 up-regulation in neuroblastoma cells lines and (3) The comparative analysis of the overexpression of human metallothionein in neuroblastoma and its impact on susceptibility to chemotherapy.

                       

Towards The Engineering Of Living Cells That Mimic Computers

Synthetic biology is challenging our current conception at multiple levels with an unprecedented potential. The aim is the (re)engineering of gene regulatory circuits to end with cells (re)programmed on purpose for biotech/biomed applications (viz., to implement novel or discover natural functions). This is accomplished by introducing suitable synthetic DNA pieces, mostly designed from scratch thanks to the acquired knowledge of molecular biology, in the target cell. But, “such engineering needs to be carried out through the combination of control mechanisms...

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