Teaching T Cells Where To Go: Immune-Derived Acetylcholine Facilitates Migration Into Infected Tissues
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Maureen Cox is a postdoctoral research fellow at the University Health Network, Department of Medical Biophysics.

                       

Teaching T Cells Where To Go: Immune-Derived Acetylcholine Facilitates Migration Into Infected Tissues

Most people think of acetylcholine as a neurotransmitter, a substance that is produced by nerve cells to relay signals between nerves as well as from nerves to muscle cells. In the brain, acetylcholine is linked to learning and attention. Recently, we have found that acetylcholine produced by certain immune cells allows them to migrate into infected tissues where they can then combat the infection, in a paper published in Science. Although acetylcholine is made in great quantities by cholinergic neurons,...

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