A Challenge For Making Hard-to-fly Stuffs Fly: An Introduction Of Simple And Effective Methods For Protein MALDI-TOF MS
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Masahiko is a research scientist at Teikyo University.

                       

A Challenge For Making Hard-to-fly Stuffs Fly: An Introduction Of Simple And Effective Methods For Protein MALDI-TOF MS

Mass spectrometry (MS) has been a powerful tool for analyzing the molecular weights of the biological components comprising our body. Biochemists routinely utilize the information of the analyzed molecular weights for detecting pathological changes (or lesions) of patients. In order to detect in MS, an analyte must be excised for ionization with the application of excessive energy, which, ironically, means that components with higher molecular weights, such as proteins, are exposed to harsh degrading environments, eventually disrupting the MS detection...

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