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Jian Wang

Dr. Jian Wang is an Associate Professor of Anesthesiology and Critical Care Medicine at the Johns Hopkins University School of Medicine. His research focuses on understanding the pathophysiology of intracerebral hemorrhage. He is also interested in translational research to identify potential therapeutic targets for treating or limiting hemorrhagic brain injury. Dr. Wang is a member of the American Society for Neuroscience, the American Heart Association, the American Stroke Association, the International Society for Cerebral Blood Flow & Metabolism, and the International Stroke Society. He is on the editorial boards of Stroke & Vascular Neurology, Phytomedicine, The Journal of Cerebral Blood Flow & Metabolism, and Brain, Behavior, & Immunity. Dr. Wang’s work has been recognized by the American Heart Association with a Scientist Development Award and by the National Institute of Health with multiple R01 grant awards.

Investigating Microglia And Macrophage Function After Intracerebral Hemorrhage And Other Brain Diseases

Intracerebral hemorrhage (ICH), one of the most common types of stroke, affects millions of people each year. During this type of stroke, also called hemorrhagic stroke, blood accumulates in the brain after a blood vessel rupture, causing severe damage. Microglia, […]

Inhibiting Prostaglandin E2 Receptor EP3 May Reduce Brain Injury After Hemorrhagic Stroke

Intracerebral hemorrhage (ICH), otherwise known as hemorrhagic stroke, accounts for approximately 15% of all strokes. In this type of stroke, high blood pressure or external brain trauma causes thin-walled arteries in the brain to tear. Blood that leaks through this […]

Inhibiting Ferroptosis — A New Hope For Intracerebral Hemorrhage Therapy

Strokes can be divided into two main subtypes — ischemic and hemorrhagic. Ischemic stroke is the more common type and is caused by a blockage to blood flow in the brain. Intracerebral hemorrhage (ICH) is caused by the rupture of […]

Pinocembrin: A Natural Compound For Treatment Of Acute Intracerebral Hemorrhage And Traumatic Brain Injury

In the past decades, hospital admissions for acute brain injury have continued to rise. For instance, intracerebral hemorrhage (ICH) and traumatic brain injury (TBI) are just two subtypes of acute brain injury that have increased in annual incidence without a […]

(−)-Epicatechin, A Natural Flavanol Compound, Protects Against Acute Brain Injuries 

(−)-Epicatechin (EC) is a natural flavanol compound found at high concentrations in green tea and cocoa.1 Recently, we and others reported that EC treatment was beneficial in animal models of ischemic stroke (caused by a blocked brain blood vessel),2 hemorrhagic […]