Small-Molecule TLR8 Antagonists And The Human Immune System
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About The Author

Hang Hubert Yin is currently a Professor and Deputy Dean of the School of Pharmaceutical Sciences at Tsinghua University. After studying for a bachelor's degree at Peking University, he received his PhD from Yale University in 2004 under the supervision of Professor Andrew Hamilton

                       

Small-Molecule TLR8 Antagonists And The Human Immune System

The human immune system is composed of the innate immune system and the adaptive immune system. The innate immune system includes epithelial tissues, immune cells, etc., which could effectively eliminate various pathogens. Given the vast amount and kinds of cells as well as proteins in humans, one major function of the immune system is differentiating between pathogen and host; this function relies mostly on pattern recognition receptors (PRR). PRRs are able to recognize specific molecular patterns that are highly conservative among...

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