About The Author

Eric M. Mukherjee, MD, PhD is a Dermatology resident at Vanderbilt University. He received his degree from the Dermatology Department at the University of Pennsylvania.

Breaking Bad: IgG4 In Autoimmunity

The human immune system is a complex network of cells and soluble factors that can cleverly adapt to combat infection.  For example, B cells rearrange and mutate their own DNA to create a vast repertoire of antibodies capable of binding to and destroying virtually any target. During B cell development, the antibody-coding genes are shuffled