About The Author

Dr Calkin’s research interests include metabolic and neuroendocrine disorders in patients with bipolar disorder. This includes examining the effects of obesity, insulin resistance and type II diabetes on course and outcome in bipolar disorder, including response to lithium and effect on brain changes on neuroimaging.

The Impact Of Insulin Resistance On The Course Of Bipolar Disorder

Type 2 diabetes is two to three times more prevalent among people with bipolar disorder than among the general population, with over half of all people with bipolar disorder having either insulin resistance (also known as “pre-diabetes”) or type 2 diabetes. The development of type 2 diabetes typically follows a progression from normal glucose metabolism