About The Author

Chao Zeng is a researcher associated with the Chinese Academy of Sciences | CAS.

SIOC Scientists Upgrade The Mechanism Of Pictet–Spengler Reactions

First discovered in 1911, the Pictet–Spengler reaction ranks among the most fundamental reactions in organic chemistry. It has found broad applications in the syntheses of indole-derived natural products and pharmaceuticals. For example, a Pictet–Spengler reaction is involved as one key step in the synthesis of Cialis, a drug for treating erectile dysfunction (ED) or benign