Protecting Neurons From The Effects Of Parkinson’s Disease
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About The Author

Boris Kantor is an Assistant Research Professor in the Department of Neurobiology at Duke University.

"Kantor Lab, the Duke University Viral Vector Core, facilitates the use of virus-mediated tools for gene transfer by investigators across diverse fields of study such as systems neuroscience, stem cell biology, metabolism, aging, cancer biology and others. Services are open to researchers within the Duke University Medical Center, Duke University, as well as outside investigators, worldwide."

                       

Protecting Neurons From The Effects Of Parkinson’s Disease

In our recent manuscript entitled Downregulation of SNCA expression by targeted editing of DNA-methylation: A potential strategy for precision therapy in PD, recently published in the journal Molecular Therapy journal (via Cell Press), we developed new therapeutic strategies targeting the regulation of SNCA expression. Elevated levels of SNCA have been implicated in the pathogenesis of Parkinson’s disease (PD). The gene encodes a protein called alpha-synuclein, which, when expressed in high levels, can be toxic as it tends to generate and be assembled in...

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