Using Fluorescent Indicators In Cancer Cells To Advance Image-guided Cancer Surgery
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About The Author

Baran D. Sumer, M.D., is the Chief of the Division of Head and Neck Oncology in UT Southwestern Medical Center's Department of Otolaryngology. Sumer is a specialist in neck  and head cancer surgery and reconstruction.Sumer also serves as the Director of the Head and Neck Oncology Disease Oriented Team at the Simmons Comprehensive Cancer Center.

                       

Using Fluorescent Indicators In Cancer Cells To Advance Image-guided Cancer Surgery

Accurate visualization is critical for cancer surgery.  A large portion of the Oncologic surgeon’s task is distinguishing normal tissue from cancer. The goal is to remove all of the tumor while minimizing damage to normal tissue. To accomplish this, researchers have attempted to target tumor-specific markers with contrast agents such as fluorescent dyes to allow tumor cells to “light up” compared to normal cells. Tumor-specific markers, however, can vary in concentration across different tumors of the same type and are...

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