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Aymen Idris

I am a pharmacologist and senior lecturer at the University of Sheffield (England, UK). The focus of my research is the development of drugs for inflammation and cancer.

Besides science, I am involved in business activities related to my research and my other passions include cycling touring, playing the piano and writing.

Drugs That Harness The Body’s Own Cannabis Are Messy But Might Be Useful

Bone fracture and pain are serious complications in patients with advanced breast and prostate cancers that have spread to the bone. Although there is an expectation that the incidence of these conditions would increase as better treatments extend the lives […]

Another Feather In The Cap Of The Breast Cancer Oncogene IKKε

There has been considerable progress in the treatment of breast cancer. Advances in diagnosis, surgery, radiotherapy, and targeted chemotherapy have transformed the lives of many breast cancer sufferers. However, these benefits have certainly not been universally shared. Breast cancer recurrence […]

A Cautionary Tale About Therapeutic Manipulation Of Bone Formation

In recent decades, there has been a significant increase in clinical efforts to develop bone anabolic agents that enhance bone regeneration by stimulating the activity of bone-forming cells, the osteoblasts. The therapeutic applications of many of bone anabolics available today […]

The Ebb And Flow Of Therapeutic Targeting Of NFκB In Cancer

Chronic inflammation increases the risk of cancer, and anti-inflammatory drugs can have significant benefits for patients in terms of quality of life – including alleviating pain and in some cases improving survival. A growing body of evidence from preclinical models suggests […]

TRAFficking Of Breast Cancer Cells To Bone

Metastasis of cancer cells to bone is common in patients suffering from advanced stages of cancers that originate in distant organs such as breast, prostate, and lungs. Once in the skeleton, cancer cells acquire “bony” characteristics that enable them to […]

The Dilemma Of Targeting NFκB For The Treatment Of Secondary Cancer In Bone

The skeleton is a common site for metastatic cancer cells originated in distant organs. Skeletal-related events such as excessive bone damage and bone pain are often diagnosed in cancer patients suffering from bone metastasis and those undergoing cancer treatments such […]

Nail Testing Detects Bone Loss In Mice: Implications For Osteoporosis And Beyond

Ageing is associated with many degenerative processes, including the gradual deterioration of the skeleton. Osteoporosis (brittle bone) is a common bone disease characterized by bone weakness and an increased risk of fractures that increases dramatically in incidence with age. The […]

Therapeutic Targeting Of Marijuana Receptors: Type 1, 2 Or Both – That Is The Question

Preparations of Cannabis Sativa L. plants (marijuana) have been used for medicinal and recreational purposes for thousands of years. Today, cannabis is one of the most abused drugs in the UK, and its medicinal use for the management of anxiety […]