Commonly Used Antihypertensive Drugs In The Treatment Of Schizophrenia Or Dementia? Let’s Talk About Kynurenic Acid
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I am a biochemist and pharmacologist with specific interest in discovering cellular mechanisms that drive drugs activity.

                       

Commonly Used Antihypertensive Drugs In The Treatment Of Schizophrenia Or Dementia? Let’s Talk About Kynurenic Acid

Schizophrenia is a chronic mental disorder, which very commonly needs lifelong treatment. Frequently patients present the paranoid form of schizophrenia, in which positive symptoms, like hallucinations and delusions, as well negative symptoms, including memory impairment can be observed. Despite continuous progress in psychiatric pharmacotherapy, negative symptoms of schizophrenia remain a great therapeutic challenge. This specifically applies to cognitive dysfunction, apathy and lack of motivation. For many years, decreased dopaminergic neurotransmission along with glutamatergic signaling hypofunction in the prefrontal cortex was...

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