Examining Cystine Crystallization In Cystinosis Patients
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I am interested in research and development in the general area of colloids and interfacial phenomena. My current work in this area spans from industrial applications in separations such as scrubbing ammonia from air to pharmaceutical applications in intravenous, ophthalmic and oral drug delivery, biomedical devices such as contact lenses, and consumer products such as sunscreens.

                       

Examining Cystine Crystallization In Cystinosis Patients

Cystinosis is a genetic disease that leads to the accumulation of cystine and the formation of intracellular crystals throughout the body, including in the kidney and cornea. The crystals form inside lysosomes because of the loss of cystine efflux transporters that result in accumulation above the solubility limit, leading to crystallization. The crystals in the kidney are hexagonal, while those in the cornea are needle-shaped and likely extracellular. The cystine crystals in the cornea are predominantly located in the stroma,...

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