Telomere Length And Hospital Stay In Patients With Schizophrenia
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Akitoyo is a researh scientist at Kobe University, Department of Psychiatry.

                       

Telomere Length And Hospital Stay In Patients With Schizophrenia

Telomeres consist of tandem repeats of TTAGGG and DNA binding proteins that form a cap to protect chromosomal termini from the loss of genetic material. The shortening of telomeres to a critical length leads to genomic instability and cellular apoptosis. In somatic cells such as leukocytes, telomeres gradually shorten with each cell division because of low telomerase activity. Meanwhile, it is also well-known that various psychiatric conditions may lead to aberrant telomere shortening beyond age effect (e.g., depression, posttraumatic stress...

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